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Related Experiment Videos

Has psoriasis its own characteristic trichogram?

A Stanimirović1, M Skerlev, T Stipić

  • 1Deutsches Medizinisches Zentrum, Ein Bokek, Dead Sea, Israel.

Journal of Dermatological Science
|July 23, 1998
PubMed
Summary
This summary is machine-generated.

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Scalp psoriasis often shows characteristic changes in hair roots, specifically increased dysplastic hairs, even without hair loss. This finding suggests dysplastic hairs are a key sign in scalp psoriasis.

Area of Science:

  • Dermatology
  • Trichology
  • Pathology

Background:

  • Scalp psoriasis is a common condition.
  • Characteristic trichogram changes in scalp psoriasis, particularly in the absence of hair loss, are not well-defined.

Purpose of the Study:

  • To investigate potential characteristic trichogram changes in patients with scalp psoriasis.
  • To determine if dysplastic hair roots are a significant finding in scalp psoriasis without clinically evident hair loss.

Main Methods:

  • A case-control study comparing 45 patients with scalp psoriasis to 60 healthy volunteers.
  • Trichogram analysis was performed to assess hair root morphology and ratios.

Main Results:

  • Patients with scalp psoriasis exhibited significantly higher proportions of dysplastic hair roots (median 50%) compared to controls.

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  • A slight increase in the telogen hair ratio was observed in the psoriasis group (median 16%).
  • No significant correlation was found between dysplastic hair proportions and patient age, sex, or disease severity/duration.

    • Conclusions:

    • Increased dysplastic hair roots are a statistically significant finding in scalp psoriasis, even without apparent hair loss.
    • Dysplastic hairs may serve as a characteristic trichogram sign for scalp psoriasis.