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Isolation and Activation of Murine Lymphocytes
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An evaluation of lectin-mediated magnetic bead cell sorting for the targeted separation of enteric bacteria

J Porter1, J Robinson, R Pickup

  • 1School of Biological Sciences, University of Liverpool, UK.

Journal of Applied Microbiology
|July 23, 1998
PubMed

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.