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Use of activated heterocyclic amines in the screening of dietary antimutagens
H Hayatsu1, S Arimoto-Kobayashi, T Negishi
1Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700, Japan. hayatsu@ph2ews.1.okayama-u.ac.jp
Mutation Research
|July 24, 1998
Abstract:
Experimental methods suitable for detecting antimutagenic substances against heterocyclic amines are described. The proposed methodology will allow identification of direct interactions between the metabolically activated form of a heterocyclic amine and an antimutagenic compound.