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Updated: Aug 19, 2026

Ex Vivo Corneal Organ Culture Model for Wound Healing Studies
Published on: February 15, 2019
Lattice corneal dystrophy: epithelial macroerosions in clear corneal grafts
1Department of Ophthalmology, Melbourne University, East Melbourne, Victoria, Australia.
Abstract:
Two sisters, aged 33 and 35, underwent uncomplicated penetrating keratoplasty for lattice corneal dystrophy type 1. Both patients, as well as their younger brother, had experienced frequent recurrent epithelial erosions prior to undergoing corneal grafting. Each sister has subsequently experienced painful, corneal epithelial macroerosions in the corneal graft, in the absence of any signs of recurrence of the lattice corneal dystrophy in the grafted tissue. With treatment each episode of macroerosion has resolved without complication. To our knowledge, this is the first report of epithelial erosions in a corneal graft without clinical evidence of recurrent lattice corneal dystrophy.

