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Levels of soluble Fas ligand in myocarditis
T Toyozaki1, M Hiroe, M Tanaka
1Division of Pathology, Institute of Pulmonary Cancer Research, Chiba University School of Medicine, Japan.
The American Journal of Cardiology
|July 25, 1998
Abstract:
Serum levels of soluble Fas ligand (sFasL) increased with the severity of congestive heart failure (p <0.01), and the percentages of apoptotic myocytes detected by in situ DNA nick-end labeling were significantly higher in the patients with increased levels of sFasL than in those with normal levels of sFasL (p <0.05). These findings indicated that sFasL may play an important role in pathogenesis of myocarditis.