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cCD79a expression in a case of plasma cell leukemia
M L Alonso1, E Rubiol, R Mateu
1Department of Hematology, Hospital de la Santa Creu i Sant Pau, Secció de Marcadors, Barcelona, Spain.
Abstract:
In the present report we analyzed the immunophenotype of the neoplastic cells in a case of primary plasma cell leukemia (PCL). We performed simultaneous analysis of bone marrow and peripheral blood samples to investigate minor phenotypic variations that could explain the tendency of a population to leave medullary compartments. No major differences were observed between the two populations. The phenotype of the malignant clone was: CD38+, CD138+, CD19-, CD56+, CD117-, CD33+, CD44 , CD49e , cCD79a+ with positive cytoplasmic stain for kappa and IgG. Our findings expands the potential uses of cCD79a to cases of PCL with atypical morphology.