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Toxicity and Pathogenicity Testing of the Insect Pest Control Fungus Metarhizium anisopliae
1U.S. Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, Florida 32561, USA
Archives of Environmental Contamination and Toxicology
|July 29, 1998
Abstract:
Renewed interest in the use of Metarhizium anisopliae and its toxins for insect control prompted the following safety assessment. A neutral extract (methylene chloride, pH 7.2), derived from M. anisopliae cultures, was evaluated for toxicity and mutagenicity using aquatic animal bioassays and the Ames test. The average LC50 of the neutral extract obtained in static, acute 96-h tests conducted with 0.05) mortalities or malformations.