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Effect of levamisole on the immune status of malnourished children
M S Prakash1, V M Rao, V Reddy
1National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania, Hyderabad, India. icmrnin@ren.nic.in
Abstract:
Levamisole is known to enhance an impaired immune response. Its function as an immunostimulant was assessed in malnourished children. A total of 26 children suffering from severe protein-calorie malnutrition were selected for the study. Serum immunoglobulins were estimated in these subjects and to assess cell-mediated immunity, enumeration of T lymphocytes and the lymphocyte proliferative response were carried out. The results show an increase in the cell-mediated immunity response in the levamisole-treated group, thereby suggesting that levamisole may help to speed the recovery of malnourished children suffering from various infections.