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A lasting change in trazodone response after non-convulsive electroshock therapy for medication-resistant senile
1Department of Psychiatry, Tohoko University School of Medicine, Sendai, Japan.
Psychiatry and Clinical Neurosciences
|July 31, 1998
Abstract:
A senile patient showed a dramatic recovery from medication-resistant depression after non-convulsive electroshock therapy (nc-EST), with a lasting change in response to trazodone, which mainly acts as a serotonin re-uptake inhibitor. This result suggests that a change in the serotonin reuptake mechanism may be involved in the effect of nc-EST on depression.