Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyalinosis cutis et mucosae: gingival involvement

E Bazopoulou-Kyrkanidou1, K I Tosios, G Zabelis

  • 1Division of Oral Pathology, Faculty of Dentistry, University of Athens, Greece.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
|July 31, 1998
PubMed
Summary

Hyalinosis cutis et mucosae, a rare genetic disorder, causes hyaline material buildup in tissues. This case highlights gingival hyperplasia as a key oral manifestation in an adult patient.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Palatal schwannoma in a young female patient: report of a case and review of the literature.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2018
Same author

Periapical lesions are not always a sequelae of pulpal necrosis: a retrospective study of 1521 biopsies.

International endodontic journal·2014
Same author

Odontogenic keratocyst expresses vascular endothelial growth factor: an immunohistochemical study.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·2009
Same author

Spindle cell hemangioma (hemangioendothelioma) of the head and neck: case report of an unusual (or underdiagnosed) tumor.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics·2007
Same author

Factor XIIIa+ dendritic cells and S-100 protein+ Langerhans' cells in adult periodontitis.

Journal of periodontal research·2004
Same author

Chimeric creatures in Greek mythology and reflections in science.

American journal of medical genetics·2001

Area of Science:

  • Genetics
  • Dermatology
  • Oral Medicine

Background:

  • Hyalinosis cutis et mucosae (lipoid proteinosis, Urbach-Wiethe disease) is a rare autosomal recessive disorder.
  • Characterized by hyaline-like substance deposition in skin, submucosa, and organs.
  • Oral manifestations include nodular, thickened mucosa, affecting lips, cheeks, palate, and tongue.

Observation:

  • A 66-year-old male patient with hyalinosis cutis et mucosae presented with significant gingival hyperplasia.
  • The hyperplasia was attributed to diffuse deposition of hyaline-like material within the gingival tissues.
  • Clinical features were compared to the same patient's presentation at age 38.

Findings:

  • Microscopic examination of gingival tissues revealed characteristic hyaline deposition.

Related Experiment Videos

  • Gingival hyperplasia is a notable, albeit less commonly reported, oral manifestation of hyalinosis cutis et mucosae.
  • Longitudinal observation demonstrated disease progression and persistent oral symptoms.

    • Implications:

    • Highlights the importance of considering rare genetic disorders in differential diagnosis of gingival hyperplasia.
    • Emphasizes the diagnostic value of microscopic analysis of gingival biopsies in suspected cases.
    • Provides insights into the long-term clinical course and oral manifestations of hyalinosis cutis et mucosae.