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Apoptosis as a criterion for sensitivity of uterine cervical adenocarcinoma to cisplatin

I Sekiguchi1, M Suzuki, M Ohwada

  • 1Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.

Oncology Reports
|July 31, 1998
PubMed

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Apoptosis01:30

Apoptosis

Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size reduction of the tissue.