Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cytokines and asthma

M B Ferreira1, A G Carlos

  • 1Immunoallergology Unit, Hospital de Santa María School of Medicine, Lisbon, Portugal.

Journal of Investigational Allergology & Clinical Immunology
|July 31, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing systemic reactions and venom immunotherapy in vespid-venom allergy: observations from a retrospective study of Portuguese patients.

European annals of allergy and clinical immunology·2024
Same author

Optimizing the use of systemic corticosteroids in severe asthma (ROSA II project): a national Delphi consensus study.

Pulmonology·2023
Same author

Unsupervised clustering to differentiate rheumatoid arthritis patients based on proteomic signatures.

Scandinavian journal of rheumatology·2023
Same author

YAP activation inhibits inflammatory signalling and cartilage breakdown associated with reduced primary cilia expression.

Osteoarthritis and cartilage·2022
Same author

Culicoides spp. found near Lusitano stud farms in mainland Portugal which may contribute for IBH studies.

Veterinary parasitology, regional studies and reports·2020
Same author

The maddening itch: an approach to chronic urticaria.

Journal of investigational allergology & clinical immunology·2014
Same journal

Safety, Adherence, and Effectiveness of an Increased Dose of Pollinex Quattro Grass and/or Olive in Real-World Practice.

Journal of investigational allergology & clinical immunology·2026
Same journal

Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Moderate-to-Severe Asthma, Type 2 Inflammation, and Nocturnal Awakenings: The MORPHEO Randomized Controlled Trial.

Journal of investigational allergology & clinical immunology·2026
Same journal

Severe Rituximab-Induced Cytokine Release Syndrome After Desensitization Successfully Treated With Tocilizumab: A Case Report.

Journal of investigational allergology & clinical immunology·2026
Same journal

Dysregulation of Mast Cell Prostaglandin in Food Anaphylaxis.

Journal of investigational allergology & clinical immunology·2026
Same journal

Extract-Negative Cofactor-Dependent Shrimp Anaphylaxis Caused by IgE Reactivity to Insoluble Muscle Proteins.

Journal of investigational allergology & clinical immunology·2026
Same journal

Antibiotic Allergy Labels in Hospitalized Patients: Results of a Multicenter Cross-Sectional Study.

Journal of investigational allergology & clinical immunology·2026
See all related articles

This review examines key cytokines in bronchial asthma, detailing their role in exacerbations and chronic airway inflammation. It also explores cytokine-based therapies aimed at counteracting asthma

Area of Science:

  • Immunology
  • Pulmonology
  • Molecular Biology

Background:

  • Bronchial asthma is a chronic inflammatory airway disease.
  • Cytokines play a crucial role in asthma pathophysiology.
  • Understanding cytokine involvement is vital for effective asthma management.

Purpose of the Study:

  • To review the primary cytokines implicated in bronchial asthma.
  • To elucidate the pathogenic roles of these cytokines in asthma.
  • To examine therapeutic strategies targeting cytokine pathways in asthma.

Main Methods:

  • Literature review of immunological and clinical studies.
  • Analysis of cytokine functions in asthma pathogenesis.
  • Evaluation of current and emerging cytokine-targeted therapies.

Related Experiment Videos

Main Results:

  • Specific cytokines are identified as key drivers of airway inflammation and asthma exacerbations.
  • Evidence supports the pathogenic role of cytokines in persistent airway remodeling.
  • Cytokine modulation presents a promising therapeutic avenue.

Conclusions:

  • Cytokines are central to the inflammatory cascade in asthma.
  • Targeting specific cytokines offers potential for novel asthma treatments.
  • Further research into cytokine-driven mechanisms is warranted.