Increasing complexity of the Ras signaling pathway

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease.

Oncogene·2013

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.

Oncogene·2009

Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility.

Cancer metastasis reviews·2009

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities.

Oncogene·2009

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.

Oncogene·2007

Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.

Molecular medicine (Cambridge, Mass.)·2002

Conditional dependency of oncogenic KRAS in driving ketone body catabolism and pancreatic cancer growth.

The Journal of biological chemistry·2026

Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin.

The Journal of biological chemistry·2026

Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance.

The Journal of biological chemistry·2026

Structure Determination Reveals the Mechanistic Basis of Mannose-6-P Signal Generation by the Dimeric Lysosomal Uncovering Enzyme NAGPA.

The Journal of biological chemistry·2026

The ubiquitin ligase LONRF2 inhibits glycolysis and malignant phenotypes in endometrial cancer through aldolase A degradation.

The Journal of biological chemistry·2026

The structure of the SufBC<sub>2</sub>D-SufE complex reveals the mechanism of sulfur transfer in bacterial Fe-S cluster assembly.

The Journal of biological chemistry·2026

Erratum: Defining the optimal imaging time point for fluorescence-lifetime-based tumor identification using the non-targeting near-infrared dye indocyanine green and post-processed high-dynamic-range images: errata.

Biomedical optics express·2026

Low-Dose Radiotherapy for Benign Achillodynia: A Single Center Experience With Prospective Follow-Up.

Cureus·2026

Microfluidic Isolation of Aptamers for Intracellular Measurement of Radio-Responsive Proteins.

Radiation (Multidisciplinary Digital Publishing Institute)·2026

Microenvironmental remodeling in FLASH radiotherapy.

Frontiers in cell and developmental biology·2026

Open Boari Flap Ureteroneocystostomy in a Radiated Pelvis: A Durable Solution for Complex Distal Ureteric Strictures.

Annals of African medicine·2026

Definitive carbon ion radiotherapy for thoracic bone and soft tissue sarcoma.

BMC cancer·2026

Related Experiment Videos

Increasing complexity of the Ras signaling pathway

Related Concept Videos

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease.

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.

Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility.

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities.

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.

Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.

Conditional dependency of oncogenic KRAS in driving ketone body catabolism and pancreatic cancer growth.

Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin.

Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance.

Structure Determination Reveals the Mechanistic Basis of Mannose-6-P Signal Generation by the Dimeric Lysosomal Uncovering Enzyme NAGPA.

The ubiquitin ligase LONRF2 inhibits glycolysis and malignant phenotypes in endometrial cancer through aldolase A degradation.

The structure of the SufBC<sub>2</sub>D-SufE complex reveals the mechanism of sulfur transfer in bacterial Fe-S cluster assembly.

Erratum: Defining the optimal imaging time point for fluorescence-lifetime-based tumor identification using the non-targeting near-infrared dye indocyanine green and post-processed high-dynamic-range images: errata.

Low-Dose Radiotherapy for Benign Achillodynia: A Single Center Experience With Prospective Follow-Up.

Microfluidic Isolation of Aptamers for Intracellular Measurement of Radio-Responsive Proteins.

Microenvironmental remodeling in FLASH radiotherapy.

Open Boari Flap Ureteroneocystostomy in a Radiated Pelvis: A Durable Solution for Complex Distal Ureteric Strictures.

Definitive carbon ion radiotherapy for thoracic bone and soft tissue sarcoma.

Related Experiment Videos

Increasing complexity of the Ras signaling pathway

Related Concept Videos

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