Endothelin-1 and Paget's bone disease: is there a link?

R Tarquini1, F Perfetto, B Tarquini

  • 1Institute of Clinica Medica IV, Unit of Internal Medicine, University of Florence, Italy.

Summary

Elevated circulating endothelin-1 (ET-1) levels were observed in patients with active Paget's bone disease, suggesting a role for this peptide in bone metabolism and potentially serving as a marker for disease activity.

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