Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An improved technique for laparoscopic highly selective vagotomy using harmonic shears

N Katkhouda1, D J Waldrep, G M Campos

  • 1Department of Surgery, Healthcare Consultation Center, University of Southern California School of Medicine, Los Angeles 90033, USA.

Surgical Endoscopy
|August 1, 1998
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Yiqi Fumai lyophilized injection on B-type natriuretic peptide levels in patients with acute decompensated ischemic heart failure: a multicenter, open-label, blinded-outcome, randomized controlled trial.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same author

Application of novel nosocomial infection prevention and control combined with intestinal probiotics in children with hand, foot and mouth disease.

JPMA. The Journal of the Pakistan Medical Association·2025
Same author

NBS-mediated <i>C</i>-selenocyanation/cyclization of enaminones with KSeCN: a mild and efficient synthesis of 2-aminoselenazoles.

Organic & biomolecular chemistry·2025
Same author

Phylogeny, morphology, and behavior of the new ciliate species <i>Stentor stipatus</i>.

bioRxiv : the preprint server for biology·2024
Same author

Construction of 5-Amino-1,2-Selenazole Scaffolds through <i>N</i>-Selenocyanation/Cyclization of Enaminones Using KSeCN.

Organic letters·2024
Same author

Molybdenum(V)-mediated switching of the C(sp<sup>2</sup>)-Se bond of phenylselenyl-functionalized arenes or heterocycles under mild conditions.

Chemical communications (Cambridge, England)·2023

Laparoscopic highly selective vagotomy (HSV) using harmonic shears offers a safe and effective treatment for intractable duodenal ulcers. This minimally invasive approach leads to rapid healing and reduced acid secretion with minimal complications.

Area of Science:

  • Gastroenterology
  • Minimally Invasive Surgery
  • Surgical Innovation

Background:

  • Classic highly selective vagotomy (HSV) outcomes are technique-dependent, with incomplete operations leading to duodenal ulcer recurrence.
  • Laparoscopic approaches to HSV are infrequently reported and often tedious due to the use of clips for neurovascular division.
  • The efficacy of laparoscopic HSV remains uncertain due to technical challenges.

Purpose of the Study:

  • To evaluate the safety and efficacy of laparoscopic extended highly selective vagotomy (HSV) using harmonic shears.
  • To assess the impact of this technique on intractable duodenal ulcers in Helicobacter pylori-negative patients.

Main Methods:

  • Ten patients with intractable duodenal ulcers and negative H. pylori status underwent laparoscopic extended HSV.

Related Experiment Videos

  • Procedures were performed using a novel surgical tool, the harmonic shears, for division of structures.
  • Standardized follow-up included endoscopy and acid secretion studies.

    • Main Results:

    • All laparoscopic procedures were completed successfully within approximately 1 hour.
    • No deaths or postoperative complications were observed; patients were discharged the next day.
    • Follow-up demonstrated complete duodenal ulcer healing, a 74% decrease in basal acid output (BAO), and a 79.2% decrease in maximal acid output (MAO).

    Conclusions:

    • Harmonic shears significantly expedite laparoscopic HSV, making the procedure more efficient.
    • Laparoscopic HSV using harmonic shears is a safe and teachable procedure with good early follow-up results.
    • This technique is an acceptable option for managing intractable, H. pylori-negative duodenal ulcers.