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Abnormal Uterine Artery Waveforms in the Second Trimester Are Associated with Adverse Pregnancy Outcome in High Risk

Morris1, Fay, Ellwood

  • 1Department of Obstetrics and Gynaecology, University of Sydney, The Nepean Hospital, Great Western Highway, Penrith, New South Wales 2750, Australia

Journal of Maternal-Fetal Investigation : the Official Journal of French Society of Ultrasound in Medicine and Biology ... [Et Al.]
|December 16, 1998
PubMed

> Objective: To establish whether uterine artery flow velocity waveforms in the second trimester are associated with adverse pregnancy outcome in women with a poor obstetric history. Methods: We reviewed the obstetric case notes of 50 women with a poor obstetric history in previous pregnancies in whom uterine artery flow velocity waveforms had been obtained at 18 weeks gestation. Results: In this population 40% had an adverse pregnancy outcome (preeclampsia, pregnancy-induced hypertension, preterm delivery, birthweight <10th percentile or perinatal death). Preeclampsia, perinatal death, and preterm delivery were all significantly associated with abnormal uterine artery waveforms at 18 weeks. Conclusions: Assessment of uterine artery flow velocity waveforms at 18 weeks gestation shows promise as a screening test in the high risk obstetric population. The technique requires formal evaluation in a prospective, double blinded study.

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