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Affective disorder associated with a balanced translocation involving chromosome 14 and 18
J Overhauser1, W H Berrettini, K Rojas
1Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Philadelphia, PA 19107, USA. J_Overhauser@lac.jci.tju.edu
Psychiatric Genetics
|August 1, 1998
Abstract:
We report a case of a women with psychiatric illness that includes bipolar disorder who has a karyotype of 46,XX,t(14;18)(q11.2;q22.1). The region on chromosome 18 that is involved in the translocation has been implicated in other families through linkage and association studies as possibly containing a gene for bipolar illness.