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Updated: Aug 10, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Open angle glaucoma and non-central retinal vein occlusion--the chicken or the egg?
1Department of Ophthalmology, Institute of Clinical Neuroscience, Göteborg University, Sweden. bertil.lindblom@oftalmologi.gu.se
Purpose:
To determine whether non-central retinal vein occlusion (nCRVO) or open angle glaucoma (OAG) is the primary event in eyes suffering from both diseases.
Methods:
The study has two parts. The first is a retrospective survey of a clinical glaucoma database. In eyes with OAG and nCRVO, the temporal relationship between the conditions was determined when possible. The second part is a ten-year follow-up study of eyes with isolated nCRVO.
Results:
Study 1: Among 576 OAG patients, 25 (4.3%) had nCRVO. In all eyes except one, OAG occurred before nCRVO. Almost without exception a vein on the optic disk or at the disk margin was occluded. Study 2: Most eyes with isolated nCRVO had an occluded vein at a retinal artery-vein crossing. Only one of 34 patients had developed OAG after ten years.
Conclusions:
This study suggests that OAG in most eyes is the primary event. nCRVO had different characteristics in eyes with OAG compared to eyes without OAG.
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