Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

""Non-communicating'' syringomyelia: a non-existent entity

W J Gardner, F G McMurray

    Surgical Neurology
    |October 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The control of bleeding during operation by induced hypotension.

    Journal of the American Medical Association·2010
    Same author

    Diagnosis of non-traumatic intracranial lesions.

    The Ohio State medical journal·2010
    Same author

    Disseminated oligodendroglioma.

    Archives of neurology and psychiatry·2010
    Same author

    Pentothal sodium anesthesia in neurologic surgery.

    The New England journal of medicine·2010
    Same author

    The use of tantalum for repair of cranial defects in infected cases.

    Cleveland Clinic quarterly·2010
    Same author

    Diagnosis of brain tumor.

    Modern medicine·2010

    Syringomyelia, a condition involving fluid-filled cavities in the spinal cord, arises from hindbrain herniation. Surgical findings reveal that even post-traumatic cases often have a communicating syrinx, challenging previous classifications.

    Area of Science:

    • Neurology
    • Neurosurgery
    • Developmental Biology

    Background:

    • Syringomyelia is characterized by a syrinx, a fluid-filled cavity within the spinal cord.
    • It is often associated with hindbrain abnormalities, such as Chiari malformation.
    • The communication between the syrinx and the fourth ventricle is a key pathological feature.

    Purpose of the Study:

    • To investigate the anatomical basis of syringomyelia, particularly the role of hindbrain herniation.
    • To clarify the communication status of syringomyelia in post-traumatic paraplegics.
    • To understand the pathomechanism of symptom development in traumatic syringomyelia.

    Main Methods:

    • Surgical observation and intraoperative findings were used to assess the communication between the syrinx and the fourth ventricle.

    Related Experiment Videos

  • Autopsy data was reviewed to compare with surgical findings regarding communication.
  • Clinical data from post-traumatic paraplegics who developed syringomyelia was analyzed.

    • Main Results:

    • Hindbrain herniation with persisting hydromyelia is identified as the anatomical substrate of syringomyelia.
    • Surgical exploration frequently reveals communication between the syrinx and the fourth ventricle, which is often missed in postmortem examinations due to shrinkage.
    • Syringomyelia developed in 16 out of 864 post-traumatic paraplegics and was surgically confirmed to be communicating, similar to non-traumatic cases.
    • Traumatic subarachnoid block exacerbates intracranial fluid pulse waves, leading to symptom development.

    Conclusions:

    • The forebrain's encroachment contributes to the development of syringomyelia by causing hindbrain herniation.
    • Communication between the syrinx and the fourth ventricle is a common feature of syringomyelia, even in post-traumatic cases.
    • Spinal blocks, both traumatic and non-traumatic, can lead to the development of syringomyelia.