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Tn5706, a transposon-like element from Pasteurella multocida mediating tetracycline resistance
C Kehrenberg1, C Werckenthin, S Schwarz
1Institut für Tierzucht und Tierverhalten der Bundesforschungsanstalt für Landwirtschaft Braunschweig-Völkenrode, 29223 Celle, Germany.
Antimicrobial Agents and Chemotherapy
|August 4, 1998
Abstract:
The 4,378-bp putative tetracycline resistance transposon Tn5706 of Pasteurella multocida consists of an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS1596 and IS1597. Two reading frames for proteins of 70 and 228 amino acids were detected in each of these insertion sequence elements. The 228-amino-acid protein revealed homology to transposase proteins of gram-positive bacteria.