Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obstetric outcome after RhD and Kell testing

S Lipitz1, A Many, S Mitrani-Rosenbaum

  • 1Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel.

Human Reproduction (Oxford, England)
|August 4, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Re: Prenatal diagnosis of umbilical-portal-systemic venous shunt associated with gestational alloimmune liver disease.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2025
Same author

Infracoccygeal/transperineal window: new method to prenatally diagnose and classify level of anal atresia.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

Predictive capacity of fetal pancreatic circumference for gestational diabetes mellitus.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

Type-I umbilical-systemic shunt with abnormal connection to azygos vein in fetus with de-novo TBX5 mutation related to Holt-Oram syndrome.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

Afferent venous perfusion of fetal liver: umbilical and portal blood-flow volumes in fetuses born small-for-gestational age.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same author

Congenital hypotonia: systematic approach for prenatal detection.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same journal

Characterizing endometriosis and adenomyosis symptom clusters and their impact on quality of life in the All of Us Research Program.

Human reproduction (Oxford, England)·2026
Same journal

A new regulatory framework: impact of the SoHO Regulation for medically assisted reproduction.

Human reproduction (Oxford, England)·2026
Same journal

Subfertility in relation to gestational weight gain and gestational diabetes: the Norwegian Mother, Father and Child Cohort Study.

Human reproduction (Oxford, England)·2026
Same journal

Pathogenic variants in ACTRT3 lead to male infertility characterized by fertilization defects.

Human reproduction (Oxford, England)·2026
Same journal

A large retrospective study on 1PN embryo transfer supports the need for updated harmonized best practice guidelines.

Human reproduction (Oxford, England)·2026
Same journal

Explainability of artificial intelligence (AI) tools in assisted reproductive technologies (ARTs): promise, clinical reality, and conceptual limits.

Human reproduction (Oxford, England)·2026
See all related articles

Molecular biology methods accurately determined fetal Rhesus D (RhD) and Kell 1 (K1) antigen status, improving management for alloimmunized pregnancies. This advance aids in predicting and treating hemolytic disease of the newborn.

Area of Science:

  • Obstetrics and Gynecology
  • Molecular Biology
  • Immunology

Background:

  • Pregnancy alloimmunization to Rhesus D (RhD) and Kell 1 (K1) antigens poses risks.
  • Accurate fetal antigen status determination is crucial for managing alloimmunized pregnancies.

Purpose of the Study:

  • To evaluate molecular biology techniques for determining fetal RhD and K1 antigen status.
  • To assess the impact of these methods on pregnancy outcomes in alloimmunized women.

Main Methods:

  • Paternal RhD genotyping via sperm DNA analysis.
  • Paternal Kell phenotyping using serologic assays.
  • Fetal RhD and K1 status determination by polymerase chain reaction (PCR) on amniotic cells.

Main Results:

Related Experiment Videos

  • Accurate prediction of fetal RhD and K1 status in 18 pregnancies.
  • Management of RhD-positive fetuses involved invasive procedures and intrauterine transfusions.
  • Successful delivery of RhD-positive and RhD-negative infants, with K1-positive fetus requiring intervention.

Conclusions:

  • Molecular biology techniques significantly advance the clinical management of RhD and Kell alloimmunization.
  • Accurate fetal genotyping enables timely interventions, improving pregnancy outcomes.