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Incessant ventricular fibrillation attacks in a patient with Brugada syndrome
M Nakamura1, M Isobe, H Imamura
1First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
International Journal of Cardiology
|August 4, 1998
Abstract:
A 42-year-old man was hospitalized for investigation of repeated episodes of ventricular fibrillation (Vf). Electrocardiogram (ECG) showed typical features of Brugada syndrome. Echocardiography, coronary angiography and endomyocardial biopsy specimen were normal. 123I-MIBG scintigraphy showed homogeneous reduction of uptake. The patient demonstrated 17 episodes of Vf in 1 day, but these were terminated by direct cardioversion. Spectral analysis of heart rate variability demonstrated increased sympathetic activity followed by Vf attacks.