Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gastric mucosal tonometry: towards new methods and applications

M G Mythen1, R Woolf, R B Noone

  • 1Department of Anaesthesia, UCLH, London, UK.

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
|August 5, 1998
PubMed
Summary

Gastrointestinal tonometry, measuring splanchnic perfusion via pHi and PrCO2, predicts outcomes in critically ill patients. The automated Tonocap system offers a significant advancement over older methods for this regional monitoring.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peri-operative care pathways: re-engineering care to achieve the 'triple aim'.

Anaesthesia·2019
Same author

Advance-care-planning and end-of-life discussions in the perioperative period: a review of healthcare professionals' knowledge, attitudes, and training.

British journal of anaesthesia·2018
Same author

Atopic dermatitis: the skin barrier and beyond.

The British journal of dermatology·2018
Same author

Effect of goal-directed haemodynamic therapy on postoperative complications in low-moderate risk surgical patients: a multicentre randomised controlled trial (FEDORA trial).

British journal of anaesthesia·2018
Same author

Erratum to: "Perioperative fluid therapy recommendations for major abdominal surgery. Via RICA recommendations revisited. Part I: Physiological background" [Rev Esp Anestesiol Reanim. 2017;64(6):328-338].

Revista espanola de anestesiologia y reanimacion·2017
Same author

Erratum to: "Fluid therapy recommendations for major abdominal surgery. Via RICA recommendations revisited. Part II: Goal directed hemodynamic therapy. Rationale for optimising intravascular volume" [Rev Esp Anestesiol Reanim. 2017;64(6):339-347].

Revista espanola de anestesiologia y reanimacion·2017

Area of Science:

  • Critical Care Medicine
  • Physiology
  • Medical Devices

Background:

  • Gastrointestinal tonometry is a minimally-invasive technique for assessing splanchnic perfusion.
  • Measurements of intramucosal pH (pHi) and regional CO2 (PrCO2) are predictive of patient outcomes.
  • Traditional tonometry methods were cumbersome and prone to errors.

Purpose of the Study:

  • To describe the automated Tonocap system for gastrointestinal tonometry.
  • To present initial experimental results from in-vitro, animal, and human studies.
  • To highlight the potential of Tonocap for clinical practice.

Main Methods:

  • Description of the Tonocap automated air-based system.
  • Review of in-vitro, animal in-vivo, and human experimental data.

Related Experiment Videos

  • Assessment of splanchnic perfusion using tonometrically derived data.

    • Main Results:

    • The Tonocap system represents an advancement in automated, on-line tonometry.
    • Experimental data supports the utility of the Tonocap system.
    • Tonometrically derived data can serve as therapeutic indices.

    Conclusions:

    • The Tonocap system simplifies gastrointestinal tonometry.
    • Widespread clinical adoption of Tonocap could enhance critical care management.
    • Further assessment of gastrointestinal tonometry's value in critically ill patients is warranted.