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Acute colitis following colonoscopy

R Caprilli1, A Viscido, G Frieri

  • 1Gastroenterology Unit, University of L'Aquila, Italy.

Endoscopy
|August 5, 1998
PubMed
Summary
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Acute colitis after colonoscopy, often caused by endoscope disinfectant glutaraldehyde, presents with severe symptoms. Patients typically recover within days, highlighting its importance in differential diagnosis.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Toxicology

Background:

  • Colonoscopy and sigmoidoscopy are common diagnostic procedures.
  • Disinfection protocols for endoscopic equipment are critical to patient safety.
  • Glutaraldehyde is a widely used high-level disinfectant for medical instruments.

Observation:

  • Three cases of severe acute colitis occurred within a week post-colonoscopy.
  • Patients presented with tenesmus, bloody diarrhea, and systemic symptoms.
  • Endoscopic findings included intense, diffuse colonic mucosal edema.

Findings:

  • The clinical presentation and endoscopic findings were consistent with glutaraldehyde-induced colitis.
  • Symptoms mimicked those of colonic ischemia.
  • All patients experienced a self-limited course, with full recovery.

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Implications:

  • Glutaraldehyde-induced colitis is a potential complication of colonoscopy.
  • Early recognition is crucial for accurate diagnosis and management.
  • This condition should be considered in the differential diagnosis of acute colitis.