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Sialographic changes in Sjögren's and SOX syndromes
N A Drage1, J E Brown, R F Wilson
1Department of Dental Radiology, Guy's Dental Hospital, United Medical School, London, United Kingdom.
Summary
Sjögren's syndrome shows more sialectasis than SOX syndrome, but neither condition involves ductal narrowing. Salivary gland imaging reveals distinct features for these conditions.
Area of Science:
- Radiology
- Rheumatology
- Otolaryngology
Background:
- Sjögren's syndrome is an autoimmune disorder affecting salivary and lacrimal glands.
- SOX syndrome is a rare condition characterized by sialadenitis, osteoarthritis, and xerostomia.
- Sialography is a key imaging technique for evaluating salivary gland structure.
Purpose of the Study:
- To compare sialographic findings in Sjögren's syndrome and SOX syndrome.
- To determine if ductal dimension changes are characteristic of these syndromes.
Main Methods:
- Sialograms from 17 Sjögren's syndrome patients, 18 SOX syndrome patients, and 19 controls were analyzed.
- Ductal diameters were measured using an A010 Solitaire Image Analysis System.
- Radiographic findings were also assessed subjectively.
Main Results:
- Sialectasis was significantly more prevalent in Sjögren's syndrome patients compared to SOX syndrome patients (p < 0.01).
- No significant differences in ductal diameter were observed among the three groups.
- Control subjects exhibited narrower main ducts than previously reported, with age-related widening of smaller ducts.
Conclusions:
- Sialectasis is not a characteristic finding in SOX syndrome.
- Ductal narrowing is not a feature of either SOX syndrome or Sjögren's syndrome based on sialographic evidence.