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Updated: Aug 3, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Abstract:
In seven cats and four dogs of different ages, an epidermoid pulmonary carcinoma has been described. This tumour originates from the orifices or the proximal sections of the ducts of the bronchial glands. The carcinoma, which usually shows no keratinization, penetrates the bronchial mucosa, submucosa and the peribronchial tissue. There is no mucus. Occasionally in the peribronchial neoplastic areas there are adenoid formations, comparable to the combined carcinoma of the WHO classification of lung tumours. Metastases have been restricted to the bronchial lymph nodes.
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