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Updated: Jul 30, 2026

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Published on: December 11, 2017
Recurrent ischemic strokes in a patient with Medtronic-Hall prosthetic aortic valve and valve strands
K Hutchinson1, F Hafeez, T D Woods
1University of Wisconsin Hospital and Clinics, Department of Medicine, Madison 53792-3248, USA.
Abstract:
Fine strands associated with prosthetic heart valves have been demonstrated with transesophageal echocardiography, but the pathologic identity of these strands is unclear. A case of a man with a prosthetic aortic Medtronic-Hall valve with prominent valve strands and recurrent strokes is discussed. The patient underwent valve replacement surgery, and histopathologic examination of the strands identified them as Lambl's excrescences.
Insights
Fine strands on prosthetic heart valves are often seen but not identified. In a patient with a Medtronic-Hall valve and strokes, these strands were confirmed as Lambl's excrescences.
Area of Science:
- Cardiovascular Pathology
- Prosthetic Heart Valve Research
- Neurology
Background:
- Transesophageal echocardiography (TEE) can visualize fine strands on prosthetic heart valves.
- The exact nature and clinical significance of these visualized strands remain incompletely understood.
Observation:
- A patient presented with a Medtronic-Hall prosthetic aortic valve exhibiting prominent valve strands.
- This patient experienced recurrent episodes of stroke, raising concern for a potential link to the valve findings.
Findings:
- Histopathologic examination of the excised valve strands definitively identified them as Lambl's excrescences.
- Lambl's excrescences are typically associated with native heart valves but were confirmed in this prosthetic valve case.
Implications:
- This case clarifies the pathologic identity of echocardiographic strands seen on prosthetic valves.
- Understanding Lambl's excrescences on prosthetic valves may improve stroke risk assessment and management in affected patients.
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Mitral Stenosis III: Medical Management
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aneurysm III: Interprofessional Care
Ischemic Stroke ll: Pathophysiology
Transient Ischemic Attack l: Introduction

