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[Nutrition and disease]

A A Pokrovskiĭ

    Voprosy Pitaniia
    |January 1, 1976
    PubMed
    Summary

    This study introduces the metabolic current theory, explaining how imbalanced nutrition at the cellular level causes disease. This concept is vital for understanding nutrition's role in disease prevention and treatment.

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    Area of Science:

    • Biochemistry and Physiology
    • Pathology
    • Nutritional Science

    Context:

    • The study explores the intricate relationship between nutrition and disease development.
    • It introduces the novel theory of metabolic current as a key mechanism for maintaining homeostasis.
    • Existing research on malnutrition, stress, and adaptive responses is analyzed within this new framework.

    Purpose:

    • To present a new conceptual framework for understanding nutrition's role in disease.
    • To analyze how nutritional imbalances at the cellular level contribute to pathogenesis.
    • To examine the influence of nutrition on adaptive responses to stressors.

    Summary:

    • The theory of metabolic current posits that imbalanced alimentation at the cellular level underlies malnutrition diseases.
    • Biochemical changes under stress and nutrition's role in adaptive reactions are analyzed.
    • The paper synthesizes author's research and global literature on nutrition, adiposity, and atherosclerosis, supporting the metabolic current concept.

    Impact:

    • Highlights the effectiveness of enzymological approaches in understanding disease.
    • Underscores the significance of the metabolic current concept for disease prevention and treatment.
    • Provides a new perspective on the etiological role of alimentary factors in various diseases.

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