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Cutaneous fibrous perineurioma
Journal of Cutaneous Pathology
|August 7, 1998
Summary
Rare perineurioma tumors of the skin were studied. These cutaneous fibrous perineuriomas, found in acral areas, share characteristics with other neurocristic tumors.
Area of Science:
- Oncology
- Dermatopathology
- Surgical Pathology
Background:
- Perineuriomas, tumors originating from perineurial cells, are uncommon.
- Existing classifications include storiform perineurial fibroma, intraneural perineurioma, and sclerosing perineurioma.
Observation:
- Two cases of cutaneous fibrous perineurioma in acral locations are presented.
- These tumors exhibited a deep, circumscribed margin and a notable vascular component.
Findings:
- Histological examination revealed small round and spindle cells.
- Immunohistochemistry showed EMA expression and membrane staining for type IV collagen.
Implications:
- Cutaneous fibrous perineuriomas represent a distinct entity within the spectrum of neurocristic tumors.
- Understanding these rare tumors aids in accurate diagnosis and classification.
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