[Radioisotopic studies in cancer of the thyroid gland]

The authors analyze the results from the carried out radioisotope investigations in preoperation and postoperation period of 42 patients with thyroid gland cancer. The test for 131J cumulation and thyreoscintigraphy were performed prior to operation. A part of the patients was stressed to reveal hyperthyroid function of the thyroid gland. The cases of cold nodules of the thyroid gland prevail on the scintigraphy. The test for 131J cumulation, thyreoscintigraphy, determination of the level of the proteinbound radioiodine in serum and Hamolski test were carried out as control investigations after the operation prior to percutaneous radiation and radioiodine therapy. Patients with hypothyroidism predominate in the first investigation. The cases with partial resection of thyroid gland prevail in scintigraphy, with cases of "white" scintigraphy and cases with normal scintigraphyic image of the gland. The proteinbound radioiodine in serum, besides the majority of the cases with normal values, in a part of the examined-shows etevated values. Homolski test in the majority of the patients is within the normal limits and the cases with elevated vales might be due to the specific changes in the capapcity-binding ability of thyroxinbinding glubin, but are always suspicious for metastases in function. The complex radioisotope investigation of the thyroid gland are basic methods for the early thyroid cancer diagnosis, for the determination of the therapeutic trends and prognosis of the patient and for the follow-up in dynamics the progress of the disease and the effect of the carried out treatment.