[Cortisol secretion rate (CSR) in hypertension and endocrine patients]

With the method of isotope dilution the circadian cortisol secretion was determined in 22 patients with hypertonic disease--28.35 mg/24 h, elevated versus CSR in healthy subjects-16.63 mg/24 h. CSR is elevated also in 5 patients with bilateral adenocortical hyperplasia and with suprarenal cancer. The patients with diencephalic syndrome, progressing according to the type of Cushing disease have elevated absolute values of CSR, but recalculated per square meter of body surface and per gram creatineine excreted in 24 h-CSR proved to be normal-about 12 mg/24 h.