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Control of cell proliferation by Myc
C Bouchard1, P Staller, M Eilers
1Institute for Molecular Biology and Tumour Research, University of Marburg, Germany. bouchard@imt.uni-marburg.de
Trends in Cell Biology
|August 8, 1998
Abstract:
Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.