Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oocyte donation: does a previous attempt affect a subsequent attempt?

S D Spandorfer1, M Moomjy, O K Davis

  • 1The Center for Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, The New York Hospital/Cornell Medical Center, New York 10021, USA.

Fertility and Sterility
|August 8, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retained products of conception as an aetiology for endometritis.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Reproductive outcomes of women aged 40 and older undergoing IVF with donor sperm.

Human reproduction (Oxford, England)·2021
Same author

Reply: Individualization of ovarian stimulation to safely optimize cycle outcomes.

Human reproduction (Oxford, England)·2020
Same author

No effect of ovarian stimulation and oocyte yield on euploidy and live birth rates: an analysis of 12 298 trophectoderm biopsies.

Human reproduction (Oxford, England)·2020
Same author

A comparison of morphokinetic markers predicting blastocyst formation and implantation potential from two large clinical data sets.

Journal of assisted reproduction and genetics·2019
Same author

A treatment algorithm for couples with unexplained infertility based on sperm chromatin assessment.

Journal of assisted reproduction and genetics·2018

Previous donor oocyte cycles do not significantly impact success rates for subsequent attempts. However, a prior delivery after the first attempt positively influences the outcome of a second oocyte donation cycle.

Area of Science:

  • Reproductive Medicine
  • Infertility Treatment
  • Assisted Reproductive Technology

Background:

  • Oocyte donation is a key assisted reproductive technology for treating infertility.
  • Understanding factors influencing success in repeat oocyte donation cycles is crucial for patient counseling and program optimization.

Purpose of the Study:

  • To evaluate the impact of prior oocyte donation attempts on the success rates of subsequent cycles.
  • To identify if previous cycle outcomes influence the effectiveness of repeat donor oocyte treatments.

Main Methods:

  • Retrospective analysis of 354 fresh oocyte donation cycles from 267 patients.
  • Clinical outcomes were stratified by attempt number (first, second, third) for each patient.
  • Pregnancy and delivery rates were calculated per retrieval and per recipient cycle.

Related Experiment Videos

Main Results:

  • Achieved an overall clinical pregnancy rate of 56.2% and an ongoing pregnancy/delivery rate of 50.3% per retrieval.
  • No statistically significant differences in outcomes were observed between the first, second, and third oocyte donation attempts.
  • Patients with a delivery after their first attempt showed a significantly higher ongoing pregnancy/delivery rate in their second attempt.

Conclusions:

  • The overall success rates for oocyte donation remain consistent across initial attempts.
  • Previous delivery success in oocyte donation cycles positively correlates with outcomes in subsequent attempts.
  • These findings provide valuable insights into the predictive value of prior outcomes in donor oocyte recipient cycles.