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Muscle strength and endurance after surgery for primary hyperparathyroidism
E B Colliander1, K Strigård, P Westblad
1Department of Orthopaedics, Huddinge University Hospital, Karolinska Institute, Sweden.
The European Journal of Surgery = Acta Chirurgica
|August 11, 1998
Summary
Surgery for primary hyperparathyroidism (HPT) did not objectively improve muscular strength or endurance. Patient-reported improvements in muscle endurance after HPT surgery are not supported by isokinetic performance measures.
Area of Science:
- Endocrinology
- Orthopedics
- Neurosurgery
Background:
- Primary hyperparathyroidism (HPT) is associated with subjective muscle weakness.
- Surgical intervention aims to correct hormonal imbalances and potentially improve patient well-being.
Purpose of the Study:
- To investigate the objective impact of surgery on muscular strength and endurance in patients with HPT.
- To compare outcomes in HPT patients with a control group undergoing thyroid resection.
Main Methods:
- Prospective study involving 9 HPT patients and 9 matched controls.
- Isokinetic testing (concentric and eccentric) at 90 degrees/second before and after surgery.
- Biochemical analysis of calcium, phosphate, TSH, and PTH levels.
Main Results:
- No significant differences in peak torque or endurance were observed before or after surgery within or between groups.
- Post-parathyroidectomy normalization of calcium and PTH did not correlate with changes in muscle performance.
- Isokinetic muscle performance remained unchanged one year after surgery.
Conclusions:
- Subjective improvements in muscle endurance reported by HPT patients post-surgery are not objectively measurable by isokinetic testing.
- Surgical correction of HPT does not lead to a demonstrable increase in muscle strength or endurance.