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Prevalence of cerebral palsy in Slovenia: birth years 1981 to 1990
1Department of Developmental Neurology, Paediatric Hospital, University Medical Centre, Ljubljana, Slovenia.
Insights
Cerebral palsy (CP) prevalence decreased in Slovenian children born between 1981-1990. Improved infant survival rates did not increase CP rates, with a notable decrease in very-low-birthweight infants.
Area of Science:
- Neurology
- Pediatrics
- Public Health
Background:
- Cerebral palsy (CP) is a group of disorders affecting movement and posture.
- Understanding trends in CP prevalence is crucial for public health planning and resource allocation.
- Slovenia has a National Cerebral Palsy Register, enabling population-based studies.
Purpose of the Study:
- To determine changes in the prevalence of cerebral palsy (CP) in Slovenian children.
- To analyze CP trends in relation to birth year, gestational age, and birth weight.
- To assess the impact of improved infant survival rates on CP prevalence.
Main Methods:
- Population-based birth-cohort study design.
- Inclusion of 768 children diagnosed with CP (aged 5-14 years) from the National Cerebral Palsy Register (1995).
- Analysis of CP prevalence per 1000 live births from 1981 to 1990, stratified by gestational age and birth weight.
Main Results:
- Total CP prevalence significantly decreased from 3.3 to 2.3 per 1000 live births between 1981 and 1990.
- The decreasing trend was observed in infants born at <= 38 weeks gestation and those weighing < 1500 g.
- CP prevalence remained stable in infants born at > 38 weeks gestation or weighing >= 2500 g. A considerable decrease in CP prevalence was noted in very-low-birthweight infants.
Conclusions:
- Improved infant survival rates in Slovenia (1981-1990) were not associated with an increase in overall CP prevalence.
- The study indicates a positive trend with a reduction in CP, particularly among high-risk infants.
- These findings suggest successful interventions or changes in care practices impacting CP rates in this cohort.
Abstract:
Changes in the prevalence of cerebral palsy (CP) in a population of Slovenian children born between 1981 and 1990 were determined. A population-based birth-cohort study was undertaken. Seven hundred and sixty-eight children with CP (aged 5 to 14 years) were identified from the National Cerebral Palsy Register in 1995. Spastic syndromes accounted for 84.8%. Of the 768 children studied, the total prevalence of CP per 1000 live births fell significantly from 3.3 in 1981 to 2.3 in 1990. This decreasing trend was observed in children born at < or = 38 weeks of gestation and in those with a birthweight of < 1500 g, but the prevalence of CP remained fairly constant in those born at > 38 weeks of gestation and in those with a birthweight of > or = 2500 g. The results show that a statistically significant improvement in the survival rate of infants born in Slovenia between 1981 and 1990 was not accompanied by an increase in the prevalence of CP. Additionally, in the group of very-low-birthweight infants the prevalence of CP considerably decreased.
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