Jove
Visualize
Contact Us

Related Experiment Videos

[T inversion in Friedreich's ataxia]

H R Ruser, I Ruser

    Zeitschrift Fur Kardiologie
    |September 1, 1976
    PubMed
    Summary

    Electrocardiogram (ECG) abnormalities, primarily T-wave inversion, are common in Friedrich's disease. However, milder forms and related ataxias show minimal ECG changes, suggesting a specific cardiac involvement in this neurodegenerative condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Clinical and experimental control of optimal therapy in epilepsy].

    Psychiatrie, Neurologie, und medizinische Psychologie·1990
    Same author

    [Clinical and psychological test studies of the psychopathology of epilepsy].

    Psychiatrie, Neurologie, und medizinische Psychologie·1990
    Same author

    [Stetho-acoustic cardiomyopathy--characteristics in cardiomyopathies studied by echocardiography].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·1989
    Same author

    Phonocardiographic diagnosis of diaphragmatic flutter.

    Journal of cardiology·1987
    Same author

    [Clinical significance of carotid-basilar anastomosis with special reference to the primitive trigeminal artery].

    Psychiatrie, Neurologie, und medizinische Psychologie·1982
    Same author

    [Experiences with cocarboxylase treatment of alcoholics in ambulatory care].

    Psychiatrie, Neurologie, und medizinische Psychologie·1980
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Neurology
    • Cardiology
    • Genetics

    Background:

    • Friedreich's ataxia is a rare inherited disease causing progressive nervous system damage.
    • Cardiac involvement, known as Friedreich's cardiomyopathy, is a significant complication.
    • Diagnostic tools for assessing cardiac impact in early or atypical presentations are crucial.

    Purpose of the Study:

    • To investigate the utility of electrocardiography (ECG) in diagnosing Friedrich's disease.
    • To differentiate cardiac findings in typical Friedrich's disease versus abortive forms and Nonne-Marie syndrome.
    • To explore the potential link between neurological and cardiac processes in the disease.

    Main Methods:

    • Retrospective analysis of electrocardiogram (ECG) findings in patients with Friedrich's disease.
    • Comparison of ECG results between patients with typical Friedrich's disease, abortive Friedrich's disease, and Nonne-Marie syndrome.
    • Review of roentgenological findings in relation to cardiac status.

    Main Results:

    • All examined patients with Friedrich's disease exhibited pathological ECG findings, predominantly T-wave inversion.
    • Patients with abortive Friedrich's disease and Nonne-Marie syndrome showed no substantial ECG alterations.
    • Roentgenological findings provided some indication of Friedreich's cardiomyopathy.

    Conclusions:

    • ECG is a sensitive indicator for cardiac pathology in typical Friedrich's disease.
    • ECG may not be reliable for detecting cardiac involvement in milder or related ataxic conditions.
    • A neuro-myo-cardiac process is a plausible explanation for Friedreich's cardiomyopathy.

    Related Experiment Videos