Related Experiment Video
Updated: Jul 29, 2026

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface
Published on: February 22, 2011
SH Reactivity of cigarette smoke and its correlation with carcinogenic effects on hamster lung cultures
Abstract:
After hamster lung cultures were exposed repeatedly to puffs of fresh smoke from 7 types of cigarettes containing variable amounts of particulate and gas vapour phase components, atypical growth and/or malignant cell transformation were observed within a period of 3-6 months. A positive correlation was demonstrable between high SH reactivity and high NO content of the gas vapour phase and malignant transformation. There was no positive correlation for the other analyzed components of the smoke, including tar content.
Related Concept Videos
Mutagenicity and Carcinogenicity
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

