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Quality control in toxicological analysis

D S Ferrara1, L Tedeschi, G Frison

  • 1Centre of Behavioural and Forensic Toxicology, Istituto di Medicina Legale, University of Padova, Italy.

Journal of Chromatography. B, Biomedical Sciences and Applications
|August 13, 1998
PubMed
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Ensuring reliable analytical toxicology results is crucial for health and social security. This review examines quality control procedures, highlighting technology

Area of Science:

  • Analytical Toxicology
  • Laboratory Quality Management

Background:

  • Professional responsibility in analytical toxicology necessitates reliable results.
  • Analytical outcomes significantly impact health and social security decisions.

Purpose of the Study:

  • To review the validity and effectiveness of quality control (QC) procedures in analytical toxicology.
  • To discuss factors influencing analytical result quality and reliability checks.
  • To present the organization of internal and external QC procedures.

Main Methods:

  • Review of quality control principles in analytical toxicology.
  • Discussion of factors affecting analytical result reliability.
  • Presentation of internal and external QC procedures.
  • Exploration of technology's role in QC improvement.

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Main Results:

  • High reliability is the essential goal for all laboratory work, irrespective of methodology.
  • Key factors contributing to analytical result quality are identified.
  • Internal and external QC procedures are detailed, including technical and organizational aspects.

Conclusions:

  • Effective quality control is paramount for dependable analytical toxicology.
  • Educational aspects and technological integration (computer, internet) can enhance QC effectiveness.
  • Continuous improvement of QC procedures is vital for professional responsibility in health and social security.