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Thrombin receptor overexpression in malignant and physiological invasion processes

S Even-Ram1, B Uziely, P Cohen

  • 1Department of Oncology, Hadassah-Hebrew University Hospital, Jerusalem, Israel.

Nature Medicine
|August 13, 1998
PubMed
Summary

Thrombin receptor (protease-activated receptor 1) is highly expressed in metastatic breast cancer and promotes tumor cell invasion. Its role in invasion is further supported by its transient expression during embryonic development.

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