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[Structural-functional changes in the thyroid gland after chronic exposure to the dioxin-containing herbicide 2,4-D]
L N Malysheva1, A A Zhavoronkov
1Research Institute of Human Morphology, Moscow.
Arkhiv Patologii
|August 14, 1998
Abstract:
White rats were given by lavage 40% solution of the herbicide 2,4-D (as an amine salt) in doses 1.0 and 0.5 mg/kg during 3 months. Destructive changes in follicles, lymphohistiocytic infiltrates, areas with morphological signs of activation (predominance of small follicles), high alkaline phosphatase and glycoproteins activity in thyrocytes were revealed.