Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional imaging by I0- and T2*-parameter mapping using multi-image EPI

O Speck1, J Hennig

  • 1Department of Radiology, University of Freiburg, Germany.

Magnetic Resonance in Medicine
|August 14, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run.

Physical review letters·2022
Same author

Pulsatility Index in the Basal Ganglia Arteries Increases with Age in Elderly with and without Cerebral Small Vessel Disease.

AJNR. American journal of neuroradiology·2022
Same author

Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.

Physical review letters·2021
Same author

Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.

Living reviews in relativity·2020
Same author

GW190521: A Binary Black Hole Merger with a Total Mass of 150  M_{⊙}.

Physical review letters·2020
Same author

Contrast-enhancement in the wall of a cerebral fusiform aneurysm in neuroborreliosis at 7 T MRI.

Journal of the neurological sciences·2020
Same journal

A Comparison of Tissue Property Values Estimated Using Conventional Cardiac MRF and MT-Cardiac MRF.

Magnetic resonance in medicine·2026
Same journal

Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.

Magnetic resonance in medicine·2026
Same journal

Triple-Pulse <sup>23</sup>Na MRI Sequence (TriNa) for Simultaneous Acquisition of Spin-Density-Weighted and Fluid-Attenuated Images.

Magnetic resonance in medicine·2026
Same journal

Evaluation of Phantom Doping Materials in Quantitative Susceptibility Mapping.

Magnetic resonance in medicine·2026
Same journal

Design of an 8-Channel Transmit 32-Channel Receive 11.7T Head Coil and Evaluation of SNR Gains.

Magnetic resonance in medicine·2026
Same journal

The Potential for Absolute Temperature Imaging Based on Brain Metabolites Using an FID-Shifting Approach in Gradient Echo Planar Spectroscopic Imaging (GREPSI).

Magnetic resonance in medicine·2026
See all related articles

Researchers developed a novel functional imaging technique to measure brain activity. This method enhances the accuracy of blood oxygenation level dependent (BOLD) signal detection by improving temporal resolution and separating inflow effects.

Area of Science:

  • Neuroimaging
  • Functional Magnetic Resonance Imaging (fMRI)
  • Biophysics

Background:

  • Accurate measurement of brain activity is crucial for understanding neurological function and disease.
  • Existing functional imaging methods face challenges in temporal resolution and distinguishing true BOLD signals from inflow artifacts.

Purpose of the Study:

  • To develop and validate a novel functional imaging method for high temporal resolution measurement of T2* and initial intensity (I0) parameter maps.
  • To improve the detection and characterization of brain activity, specifically in response to visual stimulation.

Main Methods:

  • Development of a multiecho echo-planar imaging (EPI) sequence following a single spin excitation.
  • Acquisition of multiple EPIs with increasing echo times from a single excitation.

Related Experiment Videos

  • Measurement of T2* and I0 parameter maps during primary visual stimulation in eight human subjects.

    • Main Results:

    • The new method achieved high temporal resolution in measuring T2* and I0 parameter maps.
    • Stimulation-induced increases in T2* were observed (average increase from 57.3 to 60.9 ms).
    • The technique successfully separated stimulation-induced inflow changes from true BOLD signal variations.

    Conclusions:

    • The developed functional imaging method offers a stable and information-rich approach for neuroimaging.
    • This technique enhances the ability to accurately measure BOLD signals by effectively differentiating them from inflow effects.
    • The improved methodology holds promise for more precise studies of brain function and activity.