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Multimodality magnetic resonance systems for studying free radicals in vivo
S J McCallum1, I Nicholson, D J Lurie
1Department of Biomedical Physics and Bioengineering, University of Aberdeen, Foresterhill, UK.
Physics in Medicine and Biology
|August 14, 1998
Abstract:
The multimodality approach to in vivo detection of free radicals combines the relative benefits of three free radical detection modalities: conventional RF CW-ESR, LODESR and PEDRI. We have built apparatus capable of combining these modalities to allow sequential PEDRI and CW-ESR, sequential LODESR and proton NMR imaging and simultaneous LODESR and CW-ESR. These systems offer superior performance in terms of both the scope and quality of information over single-modality free radical detection systems.