Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fluorescein angiography with an optimized filter combination

F Delori, I Ben-Sira, C Trempe

    American Journal of Ophthalmology
    |October 1, 1976
    PubMed
    Summary

    A new filter combination for fluorescein angiography improves image quality by enhancing fundus visualization and reducing scatter, particularly beneficial for older subjects. This advanced filter offers better detail in the macular area and choroidal fluorescence.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Two-point fluorophotometer for the human ocular fundus.

    Applied optics·2010
    Same author

    Direct measurement of human-cone-photoreceptor alignment.

    Journal of the Optical Society of America. A, Optics, image science, and vision·1995
    Same author

    A reflectometric technique for assessing photoreceptor alignment.

    Vision research·1995
    Same author

    Effect of partial cryoablation on retinopathy of prematurity.

    The British journal of ophthalmology·1991
    Same author

    Static and kinetic perimetry results of krypton red laser treatment for macular edema complicating branch vein occlusion.

    Annals of ophthalmology·1990
    Same author

    [Scanning laser ophthalmoscopy. Its value in macular diseases].

    Journal francais d'ophtalmologie·1990

    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Biomedical Optics

    Background:

    • Fluorescein angiography is crucial for visualizing retinal and choroidal vasculature.
    • Standard filter combinations may have limitations in demonstrating fine details and fluorescence, especially in challenging conditions.

    Purpose of the Study:

    • To develop and evaluate a novel filter combination for fluorescein angiography.
    • To assess the impact of adjusted filter transmission spectra on image quality and diagnostic information.

    Main Methods:

    • In vivo measurements of fluorescein dye's excitation and emission spectra in the fundus.
    • Characterization of a new filter combination with a 530 nm spectral separation between excitation and barrier filters.
    • Comparison of the new filters against standard filter combinations in fluorescein angiography.

    Related Experiment Videos

    Main Results:

    • The new filters enhanced film exposure across the fundus, notably in the macular area and for choroidal fluorescence.
    • Improved demonstration of choroidal vasculature and enhanced visibility of retinal detail in the macula.
    • A slight decrease in contrast for peripheral retinal vessels was observed, but overall angiogram quality improved due to better fundus visibility and reduced scatter in older subjects.

    Conclusions:

    • The novel filter combination offers significant advantages for fluorescein angiography, particularly for macular and choroidal imaging.
    • Improved visualization and reduced optical scatter enhance the diagnostic utility of angiograms, especially in elderly patients.
    • This filter advancement contributes to better assessment of ocular pathologies through improved imaging quality.