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Monozygotic twins discordant for single umbilical artery and congenital heart disease
D Nakayama1, H Masuzaki, S Yoshimura
1Department of Obstetrics and Gynecology, Nagasaki University, School of Medicine, Japan.
American Journal of Obstetrics and Gynecology
|August 15, 1998
Abstract:
We report a case of monozygotic twins. One twin had a single umbilical artery and the other co-twin had congenital heart disease. This case and a review of the literature suggest that local environmental factors are important in the pathogenesis of these malformations although genetic factors cannot be excluded.