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Related Experiment Videos

Herpes zoster in children

T Kakourou1, M Theodoridou, G Mostrou

  • 1First Department of Pediatrics, Athens University, Greece.

Journal of the American Academy of Dermatology
|August 15, 1998
PubMed
Summary

Pediatric herpes zoster (HZ) is uncommon, but early acyclovir treatment is crucial for immunocompromised children. Varicella in early childhood is a risk factor for HZ in healthy children.

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Background:

  • Clinical studies on pediatric herpes zoster (HZ) are limited.
  • Understanding HZ in children is essential due to its potential complications.

Purpose of the Study:

  • To evaluate the epidemiology, clinical features, treatment, and outcomes of HZ in pediatric patients.
  • To identify risk factors and optimal management strategies for childhood HZ.

Main Methods:

  • A study of 21 pediatric patients diagnosed with HZ using fluorescent techniques.
  • Exclusion of 5 patients with herpes simplex virus infection.
  • Systematic administration of acyclovir until no new lesions appeared.

Main Results:

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  • Thirteen patients were immunocompromised (Group A), and eight were healthy (Group B).
  • HZ duration was longer in immunocompromised children, but all patients had good outcomes.
  • Varicella in early childhood or recent exposure increased HZ risk in healthy children.

    • Conclusions:

    • Herpes simplex virus can mimic HZ; early childhood varicella is a risk factor for HZ in healthy children.
    • Acyclovir initiated within 3 days of rash onset significantly reduces morbidity and mortality in immunocompromised children with HZ.
    • Prompt diagnosis and treatment are vital for favorable outcomes in pediatric HZ cases.