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Schistosomiasis

A A El-Garem1

  • 1Cairo University, Cairo, Egypt.

Digestion
|August 15, 1998
PubMed
Summary

Schistosomiasis, a man-made parasitic disease, affects millions globally through water contact. This review covers its pathogenesis, diagnosis, treatment, and control, including vaccination research.

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Area of Science:

  • Tropical Medicine
  • Parasitology
  • Public Health

Background:

  • Schistosomiasis is a significant man-made parasitic disease prevalent in tropical and subtropical regions.
  • It affects millions worldwide, primarily linked to water contact in agricultural areas.
  • The disease is caused by a bisexual trematode with a complex life cycle involving freshwater molluscs.

Purpose of the Study:

  • To provide a comprehensive review of schistosomiasis.
  • To discuss its pathogenesis, pathology, and clinical manifestations.
  • To present current diagnostic methods, treatment strategies, control measures, and vaccination research.

Main Methods:

  • Literature review of schistosomiasis.
  • Discussion of epidemiological data and disease transmission.
  • Synthesis of information on diagnosis, treatment, and control.

Main Results:

  • Schistosomiasis pathogenesis involves parasite ova triggering cell-mediated immune reactions.
  • Key affected organs include the liver, colon, urinary bladder, and ureter, but other organs can also be involved.
  • The review details various diagnostic approaches (parasitological and immunological) and treatment options.

Conclusions:

  • Schistosomiasis presents complex challenges in pathogenesis and control.
  • Effective diagnosis, treatment, and integrated control programs are crucial.
  • Ongoing research into vaccination offers future prospects for disease eradication.

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