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Randomized prospective study of local transdermic anesthetic in fine needle aspiration biopsy for breast lumps
R de Freitas Júnior1, J A de Sousa, A C Jardim
1Department of Gynecology and Obstetrics, Medical School of the Universidade Federal de Goiás, Goiânia, Brazil.
Aim:
To evaluate the use of local transdermic anesthetics in fine needle aspiration biopsy (FNAB) in breast lesions.
Methods:
Prospective randomized study of 119 patients having breast lesions, all being indicated for FNAB. The patients were divided into three groups: 40 patients entered in the active group (lidocaine + prilocaine); 40 patients underwent the placebo group (aqueous extract of Triticum vulgaris); and a control group of 39 women in whom FNAB was performed without the administration of any substance. Both the anesthetic and placebo were administered an hour before FNAB. Pain was quantified through a visual analogic scale of pain. The type of pain was also classified in terms of occurrence: only during the puncture, only during the movements and both.
Results:
The visual linear analogic scale of pain showed an average of 3.3 in the active group, 3.5 in the placebo and 4.0 in the control group (NS). Analysis of the type of pain which was referred by the patient showed that 15% of the patients in the active group, 12.5% of those in the placebo group and 5.1% in the control group did not refer to any sensation of pain. Pain, when felt, was similar in all three groups (p < 0.4).
Conclusions:
Both the quantification and the type of pain referred to were similar in all three groups. However, there was a tendency of the patient to refer to less pain when the active substance or the placebo were used, when results were compared to the control group.