[Treatment of primary cerebral lymphoma. General principles and results]

In the SFNC series (248 patients), extension of surgical resection provided no increase in survival (p = 0.04). One hundred and twenty nine patients (52.2%) receive chemotherapy in addition to radiation therapy; 60 patients (24.3%) received radiation therapy alone, and 35 patients (14.2%) chemotherapy alone. One hundred seventeen patients (48.3%) were in remission at the conclusion of the treatment. The median survival was 12 months. Actuarial survival rates for the 248 patients at 1, 2 and 5 years after diagnosis were 48%, 37% and 27%, respectively. Treatment method provided increase in survival, and radiation therapy in addition to chemotherapy significantly enhanced the duration of survival.