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Pathological laughter following intravenous sodium valproate
1Department of Medicine (Neurology), College of Medicine, Sultan Qaboos University, Muscat, Oman.
Abstract
Background:
Pathological laughter can be a sign of epilepsy, psychiatric illness, effect of toxins or psychotropic drugs or of structural brain disease.
Method:
Case Studies.
Result:
Two patients developed inappropriate uncontrollable laughter following intravenous sodium valproate for treatment of epilepsy.
Conclusion:
Pathological laughter can be a side effect of intravenous sodium valproate.