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Updated: Aug 11, 2026

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
Minocycline-induced hepatitis with autoimmune features and neutropenia
1Department of Medicine, Christ Hospital and Medical Center, Oak Lawn, IL 60453, USA.
Abstract:
Minocycline can cause various types of hepatotoxicity. We report an 18-year-old male who developed a delayed onset of minocycline-induced cholestatic hepatitis with autoimmune features and neutropenia. He responded to withdrawal of the drug and a short course of corticosteroids. If minocycline is to be administered, then periodic monitoring for hepatoxicity is recommended.
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